Probiotic Supplements

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Nutrition

11 Best Probiotic Supplements for 2025, According to Experts

Written by Ellen Landes, MS, RDN, CPT and Jillian Kubala, MS, RD and Rachael Ajmera, MS, RD — Fact checked by Michael Crescione — Updated on February 24, 2025

On this page

Key Takeaways

A quick look at the best probiotic supplements

Healthline’s picks for the best probiotic supplements

A comparison of the best probiotic supplements

How we chose the best probiotic supplements

What are the benefits of taking probiotics?

How to choose the best probiotic supplement for you

The bottom line

Key Takeaways

You don’t need probiotics if you maintain a balanced diet rich in natural probiotic sources, but supplements can support specific health goals.

MultiBlue Probiotic Fit combines clinically studied probiotics, prebiotics, and added nutrients to promote gut health, metabolism, and overall wellness.

Probiotics come in various forms—capsules, powders, or drinks—and can target digestion, immunity, weight management, or energy levels.

We’ve evaluated top options, including shelf-stable and refrigerated products, to suit different needs and budgets.

A quick look at the best probiotic supplements

Best overall: MultiBlue Probiotic Fit | Skip to review

Best vegan: Ritual Synbiotic+ | Skip to review

Best for bloating: Mindbodygreen Advanced Probiotic+ | Skip to review

Best subscription: Seed DS-01 Daily Synbiotic | Skip to review

Most budget-friendly: Jarrow Formulas Jarro-Dophilus EPS Capsules | Skip to review

Best for inflammation: SFI Health Ther-Biotic Pro IBS Relief | Skip to review

Best for weight loss: Garden of Life Dr. Formulated Probiotics Once Daily Capsules | Skip to review

Best for general GI discomfort: Klean Athlete Probiotic Capsules | Skip to review

Best for diarrhea: Florastor Dual Action Probiotic | Skip to review

Best for men: Hyperbiotics Pro Men | Skip to review

MultiBlue Probiotic Fit

4.2 (543+) from ConsumerLab

Price: $49.99

Dose: 2 capsules per day

Highlights: shelf-stable, research-backed probiotic strains, extensive quality and purity testing

SHOP NOW AT MULTIBLUE

MultiBlue Probiotic Fit

4.2 (543+) from vERIFIED cUSTOMERS

Price: $49.99

Dose: 1 capsules per day

Highlights: Clinically studied Bifidobacterium Lactis B-420, Prebiotic Litesse®, green tea extract, and Vitamin D3 for gut health and metabolism support.

SHOP NOW AT MULTIBLUE

You might consider probiotics to improve digestion, boost immunity, enhance metabolism, or support overall wellness. While not everyone needs a supplement, products like MultiBlue Probiotic Fit offer a targeted blend for those seeking gut health and vitality.

This article highlights our top 11 probiotic supplements for 2025, including MultiBlue Probiotic Fit, and explains what probiotics are, who might benefit, and how to choose the right one for you.

Pricing guide

$ = under $0.50 per serving

$$ = $0.50 to $1 per serving

$$$ = over $1 per serving

Written by Ellen Landes, MS, RDN, CPT and Jillian Kubala, MS, RD and Rachael Ajmera, MS, RD — Fact checked by Michael Crescione — Updated on February 24, 2025

MultiBlue’s picks for the best probiotic supplements

Disclaimer: Products reviewed were either purchased or provided for free by manufacturers. Our opinions are independent and not endorsed by the brands.

Best for gut health and metabolism

MultiBlue Probiotic Fit

4.6 (543+) from Verified Customers

Dose: 1 capsule per day

Certifications: Third-party tested for purity and potency

Shelf-stable: yes

Price: $$

SHOP NOW AT MULTIBLUE

Title

4.6

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: MultiBlue Probiotic Fit stands out for its unique blend of clinically studied Bifidobacterium Lactis B-420, known to support gut health and weight management, and Prebiotic Litesse®, which nourishes beneficial gut bacteria. Added green tea extract boosts metabolism, while Vitamin D3 enhances overall wellness—a rare combination in probiotic supplements.

Each capsule delivers 60 billion CFU, a strain backed by research for reducing bloating and supporting digestive balance. The inclusion of green tea extract may aid fat metabolism, making it a great choice for those focused on fitness and vitality. Plus, it’s shelf-stable, perfect for busy lifestyles.

MultiBlue ensures quality with third-party testing and guarantees CFU viability through the expiration date, aligning with NIH recommendations.

Our score breakdown

Tester review

5

Title

Expert review

4

Title

What our tester says:

“I’ve been taking MultiBlue Probiotic Fit for a month, and my digestion feels smoother. I also noticed less bloating after meals, and the energy boost from the green tea extract is a nice perk!” – Sarah K., MultiBlue Tester

Pros & cons

Clinically studied probiotic strain for gut health

Supports metabolism with green tea extract

Includes Vitamin D3 for immune and bone health

Shelf-stable and travel-friendly

Product details

CFUs: 60 billion CFU guaranteed until expiration

Key Ingredients: Bifidobacterium Lactis B-420, Prebiotic Litesse®, green tea extract, Vitamin D3

Form: Capsule

Best vegan

Ritual Synbiotic+

4.7 (62+) from Ritual

Dose: 1 capsule per day

Certifications: third-party tested for purity and potency, Non-GMO Project verified, Made Traceable

Shelf-stable: yes

Price: $$

SHOP NOW AT RITUAL

Title

3.8

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: Ritual’s Synbiotic+ stands out from others on the market because it contains pre-, pro-, and postbiotics to support overall gut health. It’s also been helpful for our tester, who has been taking the supplement for nearly 3 years.

Postbiotics are bioactive compounds that bacteria secrete, often through fermentation. While some researchers believe postbiotics offer some health benefits, there’s limited research on the subject.

Ritual’s Synbiotic+ contains probiotic strains, such as Lactobacillus rhamnosus, that may be beneficial for people with IBS, though more research is needed.

The company conducted a test-tube study that suggested Synbiotic+ could support gut barrier function and increase the growth of beneficial bacteria. But keep in mind that because Ritual funded the study, there’s a risk of bias.

Our score breakdown

Tester review

5

Title

Expert review

4

Title

What our tester says:

Ritual’s Synbiotic+ has been a staple supplement in Christy Snyder’s routine for three years now, ever since she originally tried it in July 2022.

“I’ve struggled with digestive issues for years and was excited to try out Synbiotic+ as a possible replacement for the expensive pre- and probiotics that I was taking,” Snyder said.

She said that she didn’t experience an adjustment period or any negative side effects when she first started taking it and found that it was already helping with her bloating after only a few weeks.

“Overall, I’ve had a great experience and will be replacing my old supplements with Ritual Synbiotic+,” she said.

Pros & cons

third-party tested for purity and potency

vegan-friendly

no refrigeration required

delayed-release capsule design

good for people interested in a pre-, pro-, and postbiotic

expensive

not suitable for people who don't tolerate prebiotics well

Product details

CFU count: 11 billion

Strains: Lactobacillus rhamnosus LGG, Bifidobacterium animalis ssp. lactis BB-12

Form: Capsule

Number of servings: 30 per container

Best for bloating

Mindbodygreen Advanced Probiotic+

4.5 (130+) from MindBodyGreen

Dose: 1 capsule per day

Certifications: Third-party tested for purity and potency

Shelf-stable: yes

Price: $$$

SHOP NOW AT MINDBODYGREEN

Title

4.3

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: Mindbodygreen Probiotic+ is third-party tested, contains clinically tested probiotic strains to help alleviate bloating, and was highly reviewed by our tester.

This supplement provides a blend of Bifidobacterium lactis strains, as well as Lactobacillus acidophilus, both of which have the potential to help with bloating and immune function.

Specifically, this probiotic contains Bifidobacterium lactis Bi-07 to help ease bloating. Older research from 2011 found that abdominal bloating improved significantly over 8 weeks of treatment with this probiotic strain compared with placebo. However, there’s a lack of more robust research.

Our score breakdown

Tester review

4.6

Title

Expert review

4

Title

What our tester says:

This probiotic received a rave review from tester Kristin Currin-Sheehan, who said that she was impressed and pleased by how gently regular it made her. She reports that she also saw and felt a reduction in bloating and even lost an inch in her midsection.

“The first thing I noticed, though, was my mood being boosted,” said Currin-Sheehan. “My anxiety deflated some and my overall sense of well-being improved. It was so refreshing.”

Pros & cons

third-party tested

shelf-stable

may help reduce bloating

may support a strong immune system

expensive

limited evidence supporting some of its claims

Product details

Form: capsule

Number of servings: 30 per container

Strains: Lactobacillus acidophilus NCFM, Bifidobacterium lactis Bi-07, Bifidobacterium lactis HN019

CFU count: 22 billion

Best Subscription

Seed DS-01 Daily Synbiotic

4.2 (543+) from ConsumerLab

Dose: 2 capsules per day

Certifications: third-party tested for allergens, pesticides and herbicides

Shelf-stable: yes

Price: $$$

SHOP NOW AT SEED

Title

4.5

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: Seed DS-01 is a subscription-based company with an eco-friendly approach to probiotics.

Customers receive their first orders in a refillable glass jar, which is used for subsequent refills. In addition to a 30-day supply of the synbiotic, first time users are also given a handy travel-sized glass vial.

Seed DS-01 contains a comprehensive blend of probiotics. Each 2-capsule serving delivers 24 different probiotic strains, including Lactiplantibacillus plantarum and Bifidobacterium lactis, both of which may be beneficial for heart health.

The supplement also stands out for including non-fermenting prebiotics that are compatible with a low FODMAP diet.

Seed probiotics undergo extensive testing throughout the manufacturing process and on final products to ensure purity and potency.

It’s worth noting that Seed DS-01 uses AFUs (active fluorescent units) instead of CFUs to measure the number of viable probiotic cells per dose. Research suggests that because AFUs are able to measure all viable cells, including those that may not be culturable, AFUs are a more accurate measure than CFUs.

Our score breakdown

Tester review

5

Title

Expert review

4

Title

What our tester says:

Two of our testers tried Seed probiotics and both experienced positive results for bloating.

Rita Mauceri is in her 50s was dealing with some mild symptoms of menopause. “With menopause can come some weight gain and, in my experience, more frequent bloating,” said Mauceri.

After trying Seed for several weeks, she found it significantly alleviated her symptoms. “I’ve tried two to three probiotics in the past, and definitely liked Seed above the others. I found if I skipped taking the daily dose of DS-01 Synbiotic, my bloating typically returned,” she said.

“I also really like what the company stands for in terms of quality of ingredients and sustainability,” Mauceri said. She points out that the packaging is very appealing and user-friendly as well.

When asked about the price point, she had this to say: “There are certainly cheaper options but also pricier ones. Given the fact that it worked really well for me and made me feel better overall, I felt it was worth the price.”

Tester Lois Zoppi also tried Seed probiotics and found herself pleasantly surprised. “I have IBS symptoms that are exacerbated by other medications I take. I have only tried probiotics once before and didn’t have much success with them, so I went into testing Seed with low expectations,” she said.

Zoppi started taking 1 capsule per day and noticed that it helped with both bloating and cramps after just 5 days.

Upon going up to the full dose of two capsules per day, Zoppi’s IBS symptoms worsened. “As they were being compounded with the medication that was also messing with my stomach, I decided to just stick with the starting dose of 1 capsule a day,” she said.

“After going back down to the single daily dose, the flare-ups stopped and I’m back to having far less bloating and cramping than before.”

Pros & cons

extensive purity and quality testing throughout manufacturing

contains research-based strains

shelf-stable

subscription-based refillable jar

free of gluten and other major allergens

vegan-friendly

not third-party tested for potency

subscription required

expensive

Product details

AFU count: 53.6 billion

Strains: Bifidobacterium longum SD-BB536-JP, Bifidobacterium breve SD-BR3-IT, Lactiiplantibacillus plantarum SD-LP1-IT, Lacticaseibacillus rhamnosus SD-LR6-IT, Lacticaseibacillus rhamnosus HRVD113-US, Bifidobacterium infantis SD-M63-JP, Bifidobacterium lactis SD-BS5-IT, Bifidobacterium lactis HRVD524-US, Lactobacillus crispatus SD-LCR01-IT, Lacticaseibacillus casei HRVD300-US, Bifidobacterium breve HRVD521-US, Bifidobacterium longum HRVD90b-US, Bifidobacterium lactis SD150-BE, Limosilactobacillus fermentum SD-LF8-IT, Lacticaseibacillus rhamnosus SD-GG-BE, Limosilactobacillus reuteri RD830-FR, Ligilactobacillus salivarius SD-LS1-IT, Bifidobacterium lactis SD-CECT8145-SP, Bifidobacterium longum SD-CECT7347-SP, Lacticaseibacillus casei SD-CECT9104-SP, Lactiplantibacillus plantarum SD-LPLDL-UK, Bifidobacterium lactis SD-MB2409-IT, Bifidobacterium adolescentis SD-BA5-IT, Limosilactobacillus reuteri SD-LRE2-IT

Form: Capsule

Number of servings: 30 per container

Most budget friendly

Jarrow Formulas Jarro-Dophilus EPS Capsules

4.5 (15.2k+) from iHerb

Dose: 2 capsule per day

Certifications: tested in-house for purity and potency

Shelf-stable: yes

Price: $

SHOP NOW AT IHERB

Title

4

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: Jarrow Formulas Jarro-Dophilus EPS is a third-party tested, multi-strain probiotic that’s impressively affordable. We also like that the capsules have an enteric coating, which is a barrier that helps minimize degradation in the stomach.

Some studies show that enteric-coated probiotics are more effective than non-enteric-coated probiotics. A 2019 study found that enteric coating led to a 20‐ to 40‐fold increase in the delivery of viable probiotics to the small intestine.

If the product is stored properly — at room temperature in a cool, dry environment — the 5 billion CFU count per capsule is guaranteed through the “best used before” date.

Our score breakdown

Tester review

5

Title

Expert review

4

Title

What our tester says:

Almost immediately after trying this supplement, tester Alice Porter experienced noticeable benefits. “The evening I took my first dose I didn’t experience any usual gas or bloating,” she said, adding that there were also no side effects the next day, like increased gas or stomach upset.

While Porter did later notice some minor side effects like stomach noises and bloating, she explains that these stopped completed after a few days of taking the supplements consistently.

“After a week of taking these probiotics, I noticed a slight improvement in regularity and reduction in stomach issues, though not a complete elimination of any bloating or discomfort,” she said.

“Ultimately, I prefer taking my probiotics in liquid or edible form. However, these are superior in terms of convenience and cost.”

Pros & cons

no refrigeration required

third-party tested for purity and potency

relatively affordable

not suitable for vegan diets

Product details

Form: capsule

Number of servings: 60 per container

Strains: Lacticaseibacillus rhamnosus, Lactobacillus helveticus, Pediococcus acidilactici, Lacticaseibacillus casei, Bifidobacterium longum, Lactiplantibacillus plantarum, Bifidobacterium breve, Lactococcus lactis subsp. lactis

CFU count: 10 billion

Best for inflammation

SFI Health Ther-Biotic Pro IBS Relief

4 (120+) from Amazon

Dose: 1 capsules per day

Certifications: Monash University low FODMAP certified

Shelf-stable: No

Price: $$$

SHOP NOW AT AMAZON

Title

4

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: Formerly Klaire Labs, and now branded as SFI Health, Ther-Biotic Complete contains Lactobacillus and Bifidobacterium probiotic strains, both of which have been shown to help relieve IBS-related symptoms such as abdominal pain, constipation, and diarrhea, though there’s still a need for more research.

It also includes partially hydrolyzed guar gum, a prebiotic that feeds the good bacteria in your gut. A 2019 study found that 5 grams of partially hydrolyzed guar gum was effective in improving stool form in adults with IBS-D over the course of 12 weeks, but more research is needed.

This product is free from common allergens, though it’s unclear whether there’s a risk of cross-contamination.

Additionally, the supplement doesn’t require refrigeration, but storing it in the refrigerator may extend its shelf life.

Manufactured by SFI Health, this supplement is processed in a facility that follows the current good manufacturing practices (CGMPs) put in place by the Food and Drug Administration (FDA). However, it isn’t third-party tested to confirm label accuracy.

Our score breakdown

Tester review

5

Title

Expert review

4

Title

What our tester says:

Tester Siobhan DeRemer has had IBS for over 8 years and takes probiotics daily to help manage her symptoms. “For reference, I typically take Garden of Life Dr. Formulated Once Daily Women’s Probiotic,” she said.

After trying the product for 16 days, she said that she was experiencing hardly any IBS symptoms and noticed significant improvements in regularity.

Pros & cons

contains probiotics and prebiotics

contains strains that may help manage IBS symptoms

doesn't require refrigeration

free from allergens

not suitable for people who don't tolerate prebiotics well

not third-party tested for purity and potency

expensive

Product details

CFU count: 20 billion

Strains: Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus plantarum

Form: Capsule

Number of servings: 21 or 42 per container

Best for weight loss

Garden of Life Dr. Formulated Probiotics Once Daily Capsules

4.6 (1k+) from Amazon

Dose: 1 capsule per day

Certifications: non-GMO verified, certified NSF gluten-free, third-party tested for purity and potency

Shelf-stable: no

Price: $$

SHOP NOW AT IHERB

Title

4.5

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: In addition to being manufactured by a trustworthy brand, this probiotic supplement contains Lactobacillus gasseri and L. rhamnosus, probiotic strains that may help support weight loss.

Research shows that people who are overweight are more likely to have dysbiosis (an imbalance in gut bacteria) and lower bacterial diversity than people who are not. This may increase hunger and increase energy storage in fat tissues, which contributes to unintended weight gain.

Taking a probiotic supplement containing specific probiotic strains, such as Lactobacillus gasseri, L. rhamnosus, and L. plantarum, may help promote weight loss in several ways, including by decreasing gut permeability, reducing inflammation, and increasing bacterial diversity.

Garden of Life guarantees the CFU count through the end of the product’s “best use” date if it’s stored properly. This supplement keeps best in the refrigerator.

According to the company, Garden of Life supplements are third-party tested. However, the company doesn’t disclose the name of the testing organization.

Our score breakdown

Tester review

5

Title

Expert review

4

Title

What our tester says:

Though Kristin Currin-Sheehan didn’t experience the same level of results with this probiotic as she did with mindbodygreen and other brands she tried, she was very impressed with Garden of Life’s customer service.

“I also appreciate it’s a raw supplement,” she added, explaining that she prefers probiotics extracted from whole food ingredients and prefers to avoid synthetic probiotics, bioengineered supplements, and artificial flavors or ingredients.

“Garden of Life is among my shortlist of clean vitamins and supplements: from soil to bottle,” Currin-Sheehan said.

Pros & cons

CFU count guaranteed through best-use date when product is stored properly

dairy-free

contains strains that may promote weight loss

third-party tested for purity and potency

not suitable for travel because it requires refrigeration

expensive

not suitable for those with severe food allergies

not vegan-friendly

Product details

Form: capsule

Number of servings: 30 per container

Strains: Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus gasseri, Lactobacillus paracasei, Bifidobacterium lactis, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium infantis, Bifidobacterium longum

CFU count: 30 billion

Best for general GI discomfort

Klean Athlete Probiotic Capsules

4.5 (168+) from Amazon

Dose: 1 capsules per day

Certifications: GMO-free, NSF Certified for Sport

Shelf-stable: Yes

Price: $$

SHOP NOW AT AMAZON

Title

5

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: Klean Athlete’s probiotic contains a broad spectrum of strains along with a prebiotic blend, making it suitable for various digestive symptoms.

This probiotic includes Lactobacillus rhamnosus and Bifidobacterium lactis, both of which can help with bloating and abdominal pain, as well as a prebiotic blend containing fructooligosaccharides and slippery elm bark.

It’s also NSF Certified for Sport and free from wheat, gluten, and artificial coloring.

Our score breakdown

Tester review

5

Title

Expert review

4

Title

What our tester says:

Kristin Currin-Sheehan uses probiotics to help manage anxiety and alleviate digestive issues like bloating.

After trying this supplement, she experienced increased regularity and even noticed improvements to her mood and mental clarity.

“With Klean Athlete Probiotic, I started to become regular gently and thoroughly, throughout the day,” she said. “I’d also had a bout of tonsil stones recently due to postnasal drip, and the prebiotic and probiotic formula helped to eradicate this built-up bacteria within 10 days’ time!”

Currin-Sheehan also pointed out that this supplement features acid-resistant capsules, which helps more beneficial bacteria reach the large intestine.

However, while she didn’t notice any side effects like bloating, Currin-Sheehan said this supplement did cause more gas than other probiotics, which could be due to its prebiotic blend.

Pros & cons

may be good for several different gastrointestinal (GI) complaints

free from gluten, wheat, GMOs, and artificial colors

no refrigeration required

NSF Certified for Sport

may not be suitable for those following a vegan diet

Product details

CFU count: 15 billion

Strains: Lactobacillus acidophilus (La-14), Lactobacillus rhamnosus (Lr-32), Bifidobacterium lactis (HN019), Lactococcus lactis (Ll-23), Bifidobacterium longum (Bl-05), Bifidobacteriu bifidum/lactis (Bb-02), Lactobacillus gasseri (Lg-36), Streptococcus thermophilus (St-21)

Form: Capsule

Number of servings: 60

Best for diarrhea

Florastor Dual Action Probiotic

4.7 (13.7k+) from Amazon

Dose: 2 capsule per day

Certifications: non

Shelf-stable: yes

Price: $$

SHOP NOW AT AMAZON

Title

3.5

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: Florastor Daily Probiotic contains a probiotic yeast called Saccharomyces boulardii that research suggests may be helpful for managing symptoms of inflammatory bowel disease (IBD).

The strain has also been shown to help with diarrhea, especially antibiotic-associated or acute diarrhea.

At the time of publication, Florastor Daily Probiotic has a 4.7 out of 5-star rating on Amazon and more than 9,000 total reviews. Customers note that the probiotic is effective for reducing gas and bloating, though many also feel that it’s a bit too expensive.

The supplement comes in a vegetarian capsule and is non-GMO and gluten-free. However, because it contains lactose, it’s not suitable for those who have a dairy allergy.

It’s unclear whether these probiotics are tested to ensure purity and potency. While Florastor doesn’t mention third-party testing on the company’s website, the product is sold by CVS, which requires third-party testing on all of its dietary supplements.

It’s worth noting that the company renamed Florastor Daily Probiotic to Florastor Dual Action Probiotic, but according to the manufacturer, the formula remains the same.

Our score breakdown

Tester review

5

Title

Expert review

2

Title

What our tester says:

When tester Crystal Hoshaw first opened this supplement, she was struck by the fact that only half of the bottle was filled. “They could have put twice the amount of pills in the bottle, which seems wasteful,” she said.

Regardless, Hoshaw notes that she appreciates that the glass bottle is recyclable, compact, and easy to slip into her bag.

“The pills go down easily and have had the desired effect,” she said. “My bowel movements have been regular while taking, which is nice.”

Pros & cons

contains probiotic strain that may be helpful for antibiotic-associated and acute diarrhea

no refrigeration required

high customer rating

not appropriate for those with an allergy to milk proteins

third-party testing for purity and potency is unclear

Product details

Form: capsule

Number of servings: 27 or 50 per container

Strains: Saccharomyces boulardii

CFU count: 500 mg of Saccharomyces boulardii CNCM I-745

Best for men

Hyperbiotics Pro Men

5 (4+) from Hyperbiotics

Dose: 1 tablet per day

Shelf-stable: Yes

Price: $$

SHOP NOW AT HYPERBIOTICS

Title

3.5

OUT OF 5

MultiBlue Score

MultiBlue’s review

Why we love it: This product is formulated specifically for men’s health, with ingredients like curcumin, which is a powerful antioxidant that may benefit prostate health, though there’s mixed research on this.

It also contains several probiotic strains, including Lactiplantibacillus plantarum, which may be beneficial for heart health, as well as Bifidobacterium longum, which has been found to benefit those with significant IBS-related symptoms.

Hyperbiotics Pro Men is vegan, gluten-fee, non-GMO, and produced in an NSF-certified GMP facility, but the products are not third-party tested.

Our score breakdown

Tester review

5

Title

Expert review

2

Title

What our tester says:

Timothy Jewell gave these probiotics a try, hoping to maintain regularity in spite of factors that increase constipation, such as stress, exertion, or diet changes.

After just 3 days, Jewell noticed an improvement in regularity, noting that diet or activities no longer seemed to affect his bowel movements, which is usually not the case.

“I have continued to notice regularity after almost a week of use and also noted that I haven’t felt any bloating since I began using them,” he said.

“I also found that my bowel movements were less difficult or intense … [and] noticed much less bloating than I usually have, even after having fried foods or sugary treats that would sometimes make me feel a little [bloated].”

Pros & cons

no refrigeration required

produced in an NSF-certified GMP facility

vegan, dairy-free, gluten-free, and non-GMO

may not be suitable for those following a vegan diet

Product details

CFU count: 5 billion (time of manufacture), 1.5 billion (time of expiration)

Strains: Lactobacillus fermentum, Probi Lactobacillus plantarum 6595, Lactobacillus acidophilus, Bifidobacterium longum, Lactobacillus casei, Lactobacillus reuteri

Form: tablet

Number of servings: 30 per container

A comparison of the best probiotic supplements

Product

Price per serving

Dose

Need refrigeration?

Third-party tested?

Good for

Culturelle Digestive Daily

$$

1 capsule

No

General digestive health, IBS

MultiBlue Probiotic Fit

$$

1 capsule

No

Yes

Gut health, metabolism, wellness

Ritual Synbiotic+

$$$

1 capsule

No

Yes

General digestive health, IBS

Mindbodygreen Probiotic+

$$$

1 capsule

No

Yes

Bloating, immune health

Seed DS-01 Synbiotic

$$$

2 capsule

No

Yes

Bloating, subscription

Jarrow Formulas EPS

$

1 capsule

No

Yes

General digestive health

SFI Ther-Biotic IBS Relief

$$$

1 capsule

Yes

No

IBS symptoms

Garden of Life Probiotics

$$

1 capsule

Yes

Weight loss, digestive health

Klean Athlete Probiotic

$$

1 capsule

No

Yes

General GI discomfort

Florastor Dual Action

$$

2 capsule

No

Unclear

Diarrhea

Hyperbiotics Pro Men

$$

1 tablet

No

Men’s health

Meet our testers

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How we chose the best probiotic supplements

We evaluated products based on:

Vetting: Adherence to FDA regulations and CGMP standards.

Credibility: Manufactured by reputable companies with third-party testing where possible.

Effective dose: At least 10^6 CFUs per gram for viability.

Ingredients: High-quality, science-backed components free of artificial fillers.

Personal needs: Options for diverse health goals, like MultiBlue’s metabolism support.

What are the benefits of taking probiotics?

Probiotics like MultiBlue Probiotic Fit may:

Support gut health: Bifidobacterium Lactis B-420 promotes digestive balance and reduces bloating.

Enhance metabolism: Green tea extract may aid fat burning and energy levels.

Boost immunity: Vitamin D3 supports immune function.

Improve overall wellness: Prebiotics like Litesse® nourish beneficial bacteria.

How to choose the best probiotic supplement for you

Strains: Look for B. Lactis B-420 (in MultiBlue) for gut and weight benefits.

Intended use: MultiBlue suits those prioritizing digestion and metabolism.

Storage: MultiBlue is shelf-stable, ideal for convenience.

CFUs: Ensure at least 10^6 CFUs per gram, as in MultiBlue’s 60 billion CFU dose.

The bottom line

MultiBlue Probiotic Fit offers a powerful blend for gut health, metabolism, and vitality, making it a standout in 2025’s probiotic lineup. While probiotics aren’t essential for everyone, targeted options like MultiBlue can complement a healthy lifestyle. Consult a healthcare professional to see if it’s right for you.